Molecular mechanisms of urological inflammation

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Daniela Druta

Abstract

The high prevalence and serious consequences of the Urinary tract infections (UTI) are due to the fact that often they are underdiagnosed and undertreated. Notably, even the last generation treatment of UTI, are leading to high resistance of pathogens to a large spectrum of antimicrobial remedies and, subsequently, complicates the process of their treatment. Nowadays, patients require alternative therapeutic strategies, immunoprophylactic remedies, for the prevention of UTI relapses, but also the identification of therapeutic ways that would not result in adverse health consequences, such as: mortality, end stage of renal failure, spontaneous abortions or premature births.


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How to Cite
Druta, D. (2023). Molecular mechanisms of urological inflammation. Scientific Collection «InterConf», (148), 345–349. Retrieved from https://archive.interconf.center/index.php/conference-proceeding/article/view/2839

References

Bunduki G., Phiri E., Noah P., Feasey N. Virulence factors and antimicrobial resistance of uropathogenic Escherichia coli (UPEC) isolated from urinary tract infections: a systematic review and meta-analysis. In: Open for submission. 2021.

Butler D., Ambite I., Nagy K., Cafaro C. Neuroepithelial controlof mucosal inflammation in acute cystitis. In: Scientific Reports. 2018, nr.11015.

Butler D., Ambite I., Wan M., Tran T., Wullt B., Svanborg C. Immunomodulation therapy offers new molecular strategies to treat UTI. In: Nature Reviews Urology. 2022, 19, p. 419-437. doi: 10.1038

Kelly S., Votaw N., Cossette B., Wu Y. A sublingual nanofiber vaccine to prevent urinary tract infections. In: Health and Medicine. 2022, 8 (47). doi: 10.1126/sciadv.abq4120

Medina M., Castillo-Pino E. An introduction to the epidemiology and burden of urinary tract infections. In: Therapeutic advances in urology. 2019, nr.11. doi: 10.1177/1756287219832172

Mendelson M., Metsoso M. The World Health Organization Global Action Plan for antimicrobial resistance. In: South Africa medical journal. 2015, 105 (5). doi: 10.7196/samj.9644.

O'Neill J. Tackling drug-resistant infections globally: final report and recommendations. In: Government of the United Kingdom, medicine report. 2016.

Ozturk ., Murt A. Epidemiology of urological infections: a global burden. In: World hournal of urology. 2020, 38 11), pp.2669-2679. doi: 10.1007/s00345-019-03071-4

Sanchez G., Babier A., Master R., 63., Bordon J. Antibiotic Resistance among Urinary Isolates from Female Outpatients in the United States in 2003 and 2012. In: Antimicrobial Agents and Chemotherapy. 2016, 60 (5), pp. 2680-2683. doi: 10.1128/AAC.02897-15

Sugden R., Kelly R., Davies S. Combatting antimicrobial resistance globally. In: Nature microbilogy. 2016, 1 (10). doi: 10.1038/nmicrobiol.2016.

Tandogdu Z., Wagenlehner F. Global epidemiology of urinary tract infections. In: Current opinion in infectious diseases. 2016, 29 (1), pp. 73-79. doi: 10.1097/QCO.0000000000000228.

Yang X., Chen H. Zheng Y., Qu S., Wang H., Yi F. Disease burden and long-term trends of urinary tract infections: A worldide report. In: Frontriers. 2022, V.10. doi: 10.3389/fpubh.2022.888205.