Continuous thrombocytopenia during dengue fever inpatients, its signs, effects, and treatments, herbal medication as well as dengue infection in mosquito vector with typological aspects taking into consideration

Main Article Content

Elena Tkachenko
Jha Sahil Kumar
Bheraram Akash
Hamid Mokhtari
Liana Mokhtari
Almadaineh younes Mohammed


The dengue virus is the pathogenic illness that causes dengue (DENV). Generally speaking, dengue is an acute infectious sickness that heals on its own, but with a crucial significantly influencing phase during which patients may get well or develop a serious case. Hemodynamic abnormalities, increased vascular permeability, hypovolemia, hypotension and shock are symptoms of severe sickness. In all situations, thrombocytopenia and platelet malfunction are widespread and are associated with the treatment outcomes. Additionally, we will use a line graph to show the patients’ platelet depletion (thrombocytopenia) during dengue fever and analyze the levels of platelets during in the illness before drawing conclusions. We’ll talk about some patient reports and their experiences after overcoming dengue fever. In India, patients take herbal medications to boost platelets while simultaneously talking about the psychological effects of fever or the days following a fever.

Article Details

How to Cite
Tkachenko, E., Jha Sahil Kumar, Bheraram Akash, Mokhtari, H., Mokhtari, L., & Almadaineh younes Mohammed. (2022). Continuous thrombocytopenia during dengue fever inpatients, its signs, effects, and treatments, herbal medication as well as dengue infection in mosquito vector with typological aspects taking into consideration. Scientific Collection «InterConf», (134), 307–314. Retrieved from


Guzman MG, Harris E. Dengue. Lancet. 2015; 385: 453-465.

Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, Moyes CL, Farlow AW, Scott TW, Hay SI. Refining the global spatial limits of dengue virus transmission by evidence-based consensus. PLoS Negl Trop Dis.-2012; 6(8): e1760. Doi: 10.1371/journal.pntd.0001760.

Guo C, Zhou Z, Wen Z, Liu Y, Zeng C, Xiao D, Ou M, Han Y, Huang S, Liu D, Ye X, Zou X, Wu J, Wang H, Zeng EY, Jing C, Yang G. Global epidemiology of Dengue outbreaks in 1990-2015: A systematic review and meta-analysis. Front Cell Infect Microbiol. 2017; 7: 317. Doi: 10.3389/fcimb.2017.00317.

Jansen CC, Beebe NW. The dengue vector Aedes aegypti: what comes next. Microbes Infect. 2010; 12: 272-279.

Amarasinghe A, Kuritsk JN, Letson GW, Margolis HS. Dengue virus infection in Africa. Emerg. Infect. Dis. 2011; 17: 1349-1354.

Pancer K, Szkoda MT, Gut W. Imported cases of dengue in Poland and their diagnosis. Przegl Epidemiol.2014; 68(4):651-655.

Мищенко ВП, Мищенко ИВ. Физиология системы гемостаза. Полтава: ООО «АСМИ», 2003.

Мищенко ВП, Мищенко ИВ, Муляр ЛА. Питание, гемостаз и здоровье. Полтава, 2004.

Мищенко ВП, Мищенко ИВ. Нормальная физиология: краткий курс лекций для иностранных студентов стоматологического факультета. Изд. 2-е, доп. Полтава, 2007.

Liu Y, Liu J, Cheng G. Vaccines and immunization strategies for dengue prevention. Emerg Microbes Infect. 2016; 5(7): e77. Doi: 10.1038/emi.2016.74.

Tripathi NK, Shrivastava A. Recent developments in recombinant protein-based Dengue vaccines. Front Immunol. 2018; 9: 1919. Doi: 10.3389/fimmu.2018.01919.

Thomas SJ, Rothman AL. Trials and tribulations on the path to developing a dengue vaccine. Vaccine. 2015; 33 suppl 4: D24-31. Doi: 10.1016/j.vaccine.2015.05.095.

Thomas SJ. Dengue human infection model: re-establishing a tool for understanding dengue immunology and advancing vaccine development. Hum Vaccin Immunother. 2013;9(7): 1587-1590.

Acosta EG, Bartenschlager R. Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development. Expert Rev Vaccines. 2016;15(4): 467-482.

Wiemer D, Frickmarin H, Krüger A. Dengue fever: Symptoms, epidemiology, entomology, pathogen diagnosis and prevention. Hautarzt. 2017;68(12): 1011-1020.

Kularatne SAM, Pathirage MM-K, Kumarasiri PVR, Gunasena S, Mahindawanse SI. Cardiac complications of a dengue fever outbreak in Sri Lanka, 2005. Trans R Soc Trop Med Hyg. 2007; 101(8): 804-808.

Khongphatthanayothin A, Lertsapcharoen P, Supachokchaiwattana P, La-Orkhun V, Khumtonvong A, Boonlarptaveechoke C, Pancharoen C. Myocardial depression in dengue hemorrhagic fever: prevalence and clinical description. Pediatr Crit Care Med. 2007; 8(6): 524-529.

Arora M, Patil RS. Cardiac manifestation in Dengue fever. J Assoc Physicians. 2016; 64(7): 40-44.

Dhariwal AK, Sanzgiri PS, Nagvekar V. High degree atrioventricular block with ventricular systole in a case of dengue fever. Indian Heart J. 2016; 68: S194-S197.

Kaushik JS, Gupta P, Rajpal S, Bhatt S. Spontaneous resolution of sinoatrial exit block and atrioventricular dissociation. Singapore Med J. 2010; 51(9): e146-148.

Matthias AT, Indrakumar J, Gunatilake SB. Ventricular trigeminy in a patient with serologically confirmed dengue haemorrhagic fever. Int Arch Med. 2014; 7: 28. Doi: 10.1186/1755-7682-7-28.

Islam A, Cockroff C, Elshazly S, Ahmed J, Joyce K, Mahfuz H, Islam T, Rashid H, Laher I. Coagulopathy of Dengue and COVID-19: clinical considerations. Trop Med Infect Dis. 2022; 7(9): 210. Doi: 10.3390/tropicalmed7090210.

Most read articles by the same author(s)