Blood gas analysis in chronic obstructive pulmonary disease with pulmonary hypertension
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Abstract
This article discusses the course of pulmonary hypertension in chronic obstructive pulmonary disease, in particular the relationship between systolic pressure in the lungs and blood gases, as well as a comparative analysis of bosentan and sildenafil. The results of the study showed that in chronic obstructive pulmonary disease with pulmonary hypertension in stages II-III-IV of the disease, there are the following correlations in accordance with systolic pressure in the pulmonary artery, a positive relationship in the II degree with pCO2 (r = 0.3), (P < 0.03), negative pO2 (r = -0.3, P < 0.02), also grade III positive relationship with pC02 (r = 0.54, P < 0.001) and negative with pO2 and sO2 (r = -0.6, P < 0.001 and r = respectively).
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References
Andreassen H, Vestbo J. Chronic obstructive pulmonary disease as a systemic disease: an epidemiological perspective. Eur Respir J Suppl. 2003 Nov;46:2s-4s. doi: 10.1183/09031936.03.00000203. PMID: 14621101.
Buist AS, McBurnie MA, Vollmer WM, Gillespie S, Burney P, Mannino DM, Menezes AM, Sullivan SD, Lee TA, Weiss KB, Jensen RL, Marks GB, Gulsvik A, Nizankowska-Mogilnicka E; BOLD Collaborative Research Group. International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. Lancet. 2007 Sep 1;370(9589):741-50. doi: 10.1016/S0140-6736(07)61377-4. Erratum in: Lancet. 2012 Sep 1;380(9844):806. PMID: 17765523.
Celli BR, MacNee W; ATS/ERS Task Force. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J. 2004 Jun;23(6):932-46. doi: 10.1183/09031936.04.00014304. Erratum in: Eur Respir J. 2006 Jan;27(1):242. PMID: 15219010.
Ernazarov M., Gadaev A., Turakulov R. EARLY DIAGNOSTICS OF CARDIOGENIC LIVER DAMAGE IN PATIENTS WITH CHRONIC HEART FAILURE AND ESTIMATION OF THE EFFECTIVENESS OF TREATMENT WITH LIVERIN // InterConf. – 2021.
Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Pulmonary Disease: 2019 Report. www.goldcopd.org (Accessed on February 04, 2019).
Ismatullaevich T. R., Gadayevich G. A. Dynamics of cytokines and level of hepsidine in patients with chronic heart failure with anemia // European science review. – 2018. – no. 3-4. – S. 193-195.
Kurbonov, Abdukodir K.; Gadayev, Adigaffar G.; Ernazarov, Mukhammad M.; and Turakulov, Rustam I. (2021) "THE IMPORTANCE OF INTESTINAL MICROBIOTA AND EDOTOXINEMIA IN THE DEVELOPMENT AND COURSE OF VARIOUS HEMODYNAMIC PHENOTYPES OF CHRONIC HEART FAILURE," Central Asian Journal of Medicine: Vol. 2021 : Iss. 2, Article 2
Gadaev A.G., Gubanov A.K., Tasheva H.B., Erkenova N.A., Turakulov R.I. Principles of treatment of chronic heart failure with anemia// Bulletin of the Tashkent Medical Academy. - 2019. -№ . 2. - 18-21.
Avdeev S.N. Modern approaches to the management of patients with pulmonary hypertension. Medical Council 2014/No. 17. pp 53-59.
Belevsky A.S. Global strategy for the diagnosis, treatment and prevention of chronic obstructive pulmonary disease (revised 2014). (ed.). M., 2015. 92 p.
Martynyuk T.V. Pulmonary hypertension: diagnosis and treatment. Moscow, 2018. Series Library of the National Medical Research Center for Cardiology of the Ministry of Health of Russia.
Turakulov R.I., Sayfullayev MB., Gadaeva N. Features of differential diagnosis of anemia of chronic disease and iron deficiency anemia Comorbidities in chronic heart failure. InterConf 2020.
Chazova I.E., Avdeev S.N., Tsareva N.A., et al. Clinical guidelines for the diagnosis and treatment of pulmonary hypertension. Ter. archive 2014; 9:4-23
