Short-term impact of fasting on cardiac autonomic function: a correlative study using heart rate variability and oral glucose tolerance test data
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Abstract
Fasting is known to influence autonomic nervous system activity, but its short-term impact on cardiac autonomic function remains unclear. To evaluate the relationship between glycemic changes following fasting and heart rate variability (HRV) parameters, we analyzed publicly available data from the PLOS ONE dataset consisting of HRV metrics and oral glucose tolerance test-derived glucose concentrations. Spearman and Pearson correlation coefficients were calculated to explore associations between glucose levels and HRV indices. Moderate negative correlations were observed between glucose levels at 30 and 60 minutes and RMSSD and HF, indicating reduced parasympathetic activity during glycemic peaks. These findings suggest autonomic shifts in response to acute glycemic changes and may have implications for early metabolic risk assessment.
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References
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