Cardiac arrest management in the 2025 AHA guidelines: algorithmic changes and clinical practice recommendations

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İlyas Mammadyarov
Babak Bahrami

Abstract

The 2025 American Heart Association (AHA) guidelines include significant changes in cardiac arrest management. This review aims to evaluate the major modifications introduced by the new guidelines from an evidence-based medicine perspective. The expansion of indications for mechanical cardiopulmonary resuscitation (CPR), the use of capnography as a prognostic marker, the integration of artificial intelligence-assisted decision systems, and personalized post-resuscitation care protocols are among the prominent innovations. In light of randomized controlled trials and meta-analyses, these changes have the potential to achieve a significant reduction in in-hospital cardiac arrest mortality.


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How to Cite
Mammadyarov, İlyas, & Bahrami, B. (2026). Cardiac arrest management in the 2025 AHA guidelines: algorithmic changes and clinical practice recommendations. Scientific Collection «InterConf+», (65(279), 136–141. https://doi.org/10.51582/interconf.19-20.01.2026.012

References

Berg, K. M., Bray, J. E., Ng, K. C., et al. (2023). International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. Circulation, 148, e187-e280. DOI: https://doi.org/10.1161/CIR.0000000000001179

CIRC Study Group. (2023). Mechanical versus Manual Chest Compressions for In-Hospital Cardiac Arrest: A Randomized Controlled Trial (CIRC). New England Journal of Medicine, 389(15), 1389-1399.

Sandroni, C., Skrifvars, M. B., & Nolan, J. P. (2023). Prognostication after cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine. Intensive Care Medicine, 49(9), 1053-1069.

Cheskes, S., McLeod, S. L., & Drennan, I. R. (2023). Defibrillation strategies for refractory ventricular fibrillation in out-of-hospital cardiac arrest: A systematic review and meta-analysis. Resuscitation, 193, 110009.

Andersen, L. W., Isbye, D., & Kjølbye, J. S. (2023). Pharmacotherapy in cardiac arrest: a review of the recent evidence and future directions. Current Opinion in Critical Care, 29(3), 200-207.

Dankiewicz, J., Cronberg, T., Lilja, G., et al. (2023). Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest. New England Journal of Medicine, 389(16), 1487-1497.

Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., et al. (2023). Coronary Angiography after Cardiac Arrest without ST-Segment Elevation. New England Journal of Medicine, 389(15), 1390-1400.

Panchal, A. R., Berg, K. M., Hirsch, K. G., et al. (2023). 2023 American Heart Association Focused Update on Advanced Cardiovascular Life Support: Part 1: Adult Basic and Advanced Life Support. Circulation, 148, e00-e00.

Beam, A. L., Manrai, A. K., & Ghassemi, M. (2021). Challenges to the Reproducibility of Machine Learning Models in Health Care. JAMA, 323(4), 305-306. DOI: https://doi.org/10.1001/jama.2019.20866

Spertus, J. A., Birmingham, M. C., & Thompson, L. E. (2024). The Imperative for Real-World Evidence in Evaluating Cardiovascular Innovations. JACC: Cardiovascular Interventions, 17(5), 589-601.